Example Search Strategies

  • Should zinc be used in the treatment of acute gastroenteritis?

    Zinc AND (acute diarrhoea OR gastroenteritis OR infectious diarrhoea OR acute gastroenteritis OR diarrhea)


  • When should antibiotics be used in diarrhoeal illness?

    (acute diarrhoea OR gastroenteritis OR infectious diarrhoea OR acute gastroenteritis) AND (antibiotics or antimicrobials)


  • What antibiotics are appropriate in acute dysentery?

    (Dysentery OR bloody diarrhoea OR shigella) AND antibiotics


  • What is the evidence behind continued oral / breastfeeding as a co-intervention in acute infectious diarrhoea?

    (feeding OR breastfeeding OR breastmilk) AND (acute diarrhoea OR gastroenteritis OR infectious diarrhoea OR acute gastroenteritis OR diarrhea)


  • What is the optimal feeding regime in persistent diarrhoea?

    (feeding OR refeeding OR nutrition OR diet OR supplemental feeds OR supplemental feeding OR caloric intake OR lactose reduced OR lactose free) AND (persistent diarrhoea OR chronic diarrhoea OR intestinal infection)


  • In children with diarrhoea and dehydration without shock, is rehydration by the nasogastric route as effective as fluid given intravenously?

    (Intravenous fluids OR intravenous rehydration OR parenteral rehydration OR fluid therapy OR infusions OR nasogastric fluids OR enteral fluids OR NG fluids) AND (acute diarrhoea OR gastroenteritis OR infectious diarrhoea OR acute gastroenteritis OR diarrhea OR dehydration OR acute dehydration)

  • What antimalarials are appropriate for the management of uncomplicated malaria in areas of falciparum resistance?

    Malaria AND (therapy OR antimalarials OR falciparum OR chloroquine resistance OR multi-drug resistant malaria)


  • What adjuvant therapies are beneficial in malaria?

    (malaria OR severe malaria) AND adjuvant therapy OR adjunctive therapy OR heparin OR steroids OR dextran OR mannitol)

  • When should a blood transfusion be given to children with severe malaria?

    (severe malaria OR malaria) AND (blood transfusion OR transfusion OR whole blood OR packed cells)

  • What are appropriate fluids to use in the management of severe malaria?

    (severe malaria OR malaria) AND (fluid therapy OR i.v. fluids OR cerebral oedema OR coma OR maintenance fluids)


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